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Department of botany
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Phone: +420 585 634 801

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Přírodovědecká fakulta UPOL

Mgr. Michaela Švécarová, Ph.D.


  * 1983, Prostějov
mail to Michaela Švécarová
  Phone: 585 634 811


  • 2003-2006 Bachelor’s program in Biochemistry, Palacky University in Olomouc; Thesis topic: Determination of biogenic amines in biological fluids
  • 2006-2008 Master’s program in Biochemistry, Palacky University in Olomouc; Thesis topic: Immobilization of trypsin on magnetic nanoparticles and their application in proteomics
  • Postgraduate studies in Biochemistry at the Department of Biochemistry, Faculty of Science, Palacky University in Olomouc; Thesis topic: Immobilization of proteins on magnetic nanoparticles and their practical applications (supervisor prof. Marek Šebela)

Professional experience

  • 2009-2011 Faculty of Science, Olomouc; Department of Biochemistry, researcher
  • 2010-2012 Department of Protein Biochemistry and Proteomics; Centre of the Region Hana for Biotechnological and Agricultural Research, Faculty of Science, Olomouc, researcher
  • 2013-2014 Faculty of Science, Olomouc; Department of Cell Biology and Genetics, researcher
  • 2014 - until now Faculty of Science, Olomouc; Department of Botany, teaching assistant

Membership in Scientific Societies

  • Czech Chemical Society

Study abroad

  • Short-term research stay at the Department of Biological Chemistry, University of Padua, Italy; 3 months (supervisor prof. Fabio Vianello)

Training course

  • 18. – 22. November 2013; SafeSciMET – course 3.5: Mutagenesis and Carcinogenesis, University of Vienna, Austria
  • 3. – 7. February 2014; SafeSciMET – course 4.3: Predictive Cell Culture Systems, Martin-Luther-University Halle-Wittenberg, Germany

Conference reports

  • 2008: 7th International Conference on Scientific and Clinical Application of Magnetic Carriers, Vancouver, Canada, (poster)
  • 2008: 21st Joint Congress of the Czech and Slovak Societies for Biochemistry and Molecular Biology, Budweis, Czech Republic, (poster)
  • 2009: 61st Chemical congress, Tatranske Matliare, Slovakia, (poster)
  • 2010: 8th International Conference on the Scientific and Clinical applications of Magnetic Carriers, Rostock, Germany, (poster)
  • 2010: 62st Chemical congress, Pardubice, Czech Republic, (poster)
  • 2010: 4th Central and Eastern European Proteomic Conference meets International Metabolomics Austria, Vienna, Austria, (poster)
  • 2011: IMAGINENANO Bringing together Nanoscience & Nanotechnology, Bilbao, Spain, (posters)
  • 2012: 64st Chemical congress, Olomouc, Czech Republic, (lecture)
  • 2013: XXVII. Xenobiochemical symposium, Pavlov, Czech Republic, (poster)
  • 2014: 20th International Symposium on Microsomes and Drug Oxidations, Stuttgart, Germany, (poster)


  • Hašler, P. , Ondřej, V. , Švécarová, M. , Sedlářová, M. , Vaidová, M., Poulíčková, A. (2017):Tritium influence on morphology, reactive oxygen species production and catalase gene expression in Pseudendoclonium basilense and Stigeoclonium nanum (Chlorophyta). Fottea 17(1): 127–135. DOI: 10.5507/fot.2017.012
  • Dvořák, Z., Srovnalová, A., Švécarová, M. , Vrzal, R.(2014):The effect of anthocyans on the expression of selected phase II xenobiotic-metabolizing enzymes in primary cultures of human hepatocytes. - Food Funct. 5: 2145-2151.
  • Novotná, A., Srovnalová, A., Švécarová, M. , Korhonová, M, Bartoňková, I., Dvořák, Z.(2014):Differential Effects of Omeprazole and Lansoprazole Enantiomers on Aryl Hydrocarbon Receptor in Human Hepatocytes and Cell Lines. - Plos One, e98711.
  • Srovnalová, A., Švécarová, M. , Kopečná-Zapletalová, M., Anzenbacher, P., Bachleda, P., Anzenbacherová, E., Dvořák, Z.(2014):Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9 and CYP3A4 in primary human hepatocytes and human liver microsomes. - J. Agric. Food Chem. 62, 789-797.
  • Novotná, A., Kameníčková, A., Švécarová, M. , Korhonová, M, Bartoňková, I., Dvořák, Z.(2014):Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines. - Chem-Biol Interact 208: 64-76.
  • Kameníčková, A., Švécarová, M. , Bachleda, P., Dvořák, Z.(2013):Effects of artificial sweeteners on the AhR- and GR-dependent CYP1A1 expression in primary human hepatocytes and human cancer cells. - Toxicol in Vitro 27: 2283-2288.
  • Švécarová, M. , Šebela, M., Marková, Z., Poláková, K., Čuda, J., Šafářová, K., Zbořil, R.(2013):Thermostable trypsin conjugates immobilized to biogenic magnetite show a high operational stability and remarkable reusability for protein digestion. - Nanotechnology 24: 125102.
  • Švécarová, M. , Zajoncová, L., Poláková, K., Čuda, J, Šafaříková, M., Šebela, M., Šafařík, I.(2011):Biologically active compounds immobilized on magnetic carriers and their utilization in biochemistry and biotechnology. - Chem. Listy 105(7): 524-530.
  • Kluchova, K., Zboril, R., Tucek, J., Švécarová, M. , Zajoncova, L., Safarik, I., Mashlan, M., Markova, I., Jancik, D., Sebela, M., Bartonkova, H., Bellesi, V., Novak, P., Petridis, D.(2009):Superparamagnetic maghemite nanoparticles from solid-state synthesis – Their functionalization towards peroral MRI contrast agent and magnetic carrier for trypsin immobilization. - Biomaterials 30(15): 2855-2863.
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